{"id":5542,"date":"2023-09-23T06:16:16","date_gmt":"2023-09-23T06:16:16","guid":{"rendered":"https:\/\/sinohemedtour.com\/?p=5542"},"modified":"2024-09-04T08:04:32","modified_gmt":"2024-09-04T08:04:32","slug":"preimplantation-genetic-diagnosis-pgd","status":"publish","type":"post","link":"https:\/\/sinohemedtour.com\/?p=5542","title":{"rendered":"Preimplantation Genetic Diagnosis (PGD)"},"content":{"rendered":"<section class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text]<\/p>\n<p dir=\"ltr\"><strong>Preimplantation Genetic Diagnosis (PGD)<\/strong><\/p>\n<p dir=\"ltr\"><a href=\"https:\/\/sinohemedtour.com\/wp-content\/uploads\/2023\/09\/zz1.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-7135\" src=\"https:\/\/sinohemedtour.com\/wp-content\/uploads\/2023\/09\/zz1.jpg\" alt=\"\" width=\"500\" height=\"333\" srcset=\"https:\/\/sinohemedtour.com\/wp-content\/uploads\/2023\/09\/zz1.jpg 500w, https:\/\/sinohemedtour.com\/wp-content\/uploads\/2023\/09\/zz1-300x200.jpg 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/a><\/p>\n<p dir=\"ltr\">Pre-implantation genetic diagnosis (PGD) is a laboratory procedure used in conjunction with\u00a0in vitro fertilization (IVF)\u00a0to reduce the risk of passing on inherited conditions. Some of the most common reasons for PGD are specific single-gene conditions (such as cystic fibrosis or sickle cell anemia) and structural changes of a parent&#8217;s chromosomes. Families may also use PGD when a member of the family needs a bone marrow donor, as a way to have a child who can provide matching stem cells.<\/p>\n<p dir=\"ltr\">Typically, couples in need of these techniques are not\u00a0infertile\u00a0but have a family history of a condition and want to reduce the risk of having another child with significant health issues or early death. Through generally available genetic screening, however, occasionally couples who are seeking fertility treatment are found to be at risk of passing on an inherited condition, and PGD may be an option for them.<\/p>\n<p dir=\"ltr\">PGD is available for almost any inherited condition for which the exact mutation is known. A unique test must be developed for each couple, however. This test design may take up to several months to complete before beginning an IVF cycle.<\/p>\n<p dir=\"ltr\"><strong>\u00a0<\/strong><\/p>\n<p dir=\"ltr\"><strong><a href=\"https:\/\/sinohemedtour.com\/wp-content\/uploads\/2023\/09\/zz2.png\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-7134\" src=\"https:\/\/sinohemedtour.com\/wp-content\/uploads\/2023\/09\/zz2.png\" alt=\"\" width=\"567\" height=\"709\" srcset=\"https:\/\/sinohemedtour.com\/wp-content\/uploads\/2023\/09\/zz2.png 567w, https:\/\/sinohemedtour.com\/wp-content\/uploads\/2023\/09\/zz2-240x300.png 240w\" sizes=\"(max-width: 567px) 100vw, 567px\" \/><\/a><\/strong><\/p>\n<p dir=\"ltr\"><strong>The Different Types of PGD Available.<\/strong><\/p>\n<ul dir=\"ltr\">\n<li>Comprehensive Chromosomal Screening (CCS)\u00a0where all chromosomes are evaluated to make sure that there are 2 of all chromosomes present \u2013plus an XY for a male or an XX for a female embryo.<\/li>\n<li>Limited chromosomal screening\u00a0\u2013typically looking at 3 to 5 chromosomes (usually X, Y, and 21).\u00a0 This can evaluate sex chromosomal abnormalities and chromosomal 21 abnormalities (Down\u2019s Syndrome).<\/li>\n<li>Single Gene Disorders.\u00a0\u00a0\u00a0 This is used when there is a genetic disorder that runs in a family and when one of the patients undergoing IVF is found to be a carrier or affected by this gene.\u00a0 \u00a0In order to prevent this disease from affecting other individuals, PGD can be done to select those embryos that do not carry the affected gene.\u00a0 Examples of single gene disorders include: cystic fibrosis, sickle cell disease, thallasemia, Tay-sachs disease, Huntington disease, and many others.\u00a0 Almost any genetic disorder that can be linked to a specific gene can by identified using PGD<\/li>\n<\/ul>\n<p dir=\"ltr\"><strong>\u00a0<\/strong><\/p>\n<p dir=\"ltr\"><strong><a href=\"https:\/\/sinohemedtour.com\/wp-content\/uploads\/2023\/09\/zz3.png\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-7133\" src=\"https:\/\/sinohemedtour.com\/wp-content\/uploads\/2023\/09\/zz3.png\" alt=\"\" width=\"1080\" height=\"1920\" srcset=\"https:\/\/sinohemedtour.com\/wp-content\/uploads\/2023\/09\/zz3.png 1080w, https:\/\/sinohemedtour.com\/wp-content\/uploads\/2023\/09\/zz3-169x300.png 169w, https:\/\/sinohemedtour.com\/wp-content\/uploads\/2023\/09\/zz3-576x1024.png 576w, https:\/\/sinohemedtour.com\/wp-content\/uploads\/2023\/09\/zz3-768x1365.png 768w, https:\/\/sinohemedtour.com\/wp-content\/uploads\/2023\/09\/zz3-864x1536.png 864w\" sizes=\"(max-width: 1080px) 100vw, 1080px\" \/><\/a><\/strong><\/p>\n<p dir=\"ltr\"><strong>Who Can Benefit from PGD?<\/strong><\/p>\n<p dir=\"ltr\">PGD can benefit any couple at risk for passing on a genetic disease or condition.\u00a0 The procedure is performed prior to implantation so the need for amniocentesis later in pregnancy is reduced or negated.\u00a0 Mostly commonly PGD is used by women age 35 and over, carriers of genetic disorders, women experiencing recurrent pregnancy loss, or any patient desiring to ensure the transfer of chromosomally normal embryos.\u00a0\u00a0\u00a0 Some couples will also use PGD for family balancing or gender selection which like any form of PGD has an important medical utility to avoid sex chromosome-linked diseases like hemophilia and Duchenne\u2019s muscular dystrophy<\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text] Preimplantation Genetic Diagnosis (PGD) Pre-implantation genetic diagnosis (PGD) is a laboratory procedure used in conjunction with\u00a0in vitro fertilization (IVF)\u00a0to reduce the risk of passing on inherited conditions. Some of the most common reasons for PGD are specific single-gene conditions (such as cystic fibrosis or sickle cell anemia) and structural changes of a parent&#8217;s chromosomes. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":5515,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[296],"tags":[],"_links":{"self":[{"href":"https:\/\/sinohemedtour.com\/index.php?rest_route=\/wp\/v2\/posts\/5542"}],"collection":[{"href":"https:\/\/sinohemedtour.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sinohemedtour.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sinohemedtour.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sinohemedtour.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5542"}],"version-history":[{"count":2,"href":"https:\/\/sinohemedtour.com\/index.php?rest_route=\/wp\/v2\/posts\/5542\/revisions"}],"predecessor-version":[{"id":7136,"href":"https:\/\/sinohemedtour.com\/index.php?rest_route=\/wp\/v2\/posts\/5542\/revisions\/7136"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sinohemedtour.com\/index.php?rest_route=\/wp\/v2\/media\/5515"}],"wp:attachment":[{"href":"https:\/\/sinohemedtour.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5542"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sinohemedtour.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5542"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sinohemedtour.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5542"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}